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Food and Drug Administration (FDA) officially approved the GLP-1 medication Ozempic to help reduce the risk of worsening kidney disease in adults with type 2 diabetes and chronic kidney disease

Reactive oxygen species are a common factor in different molecular pathways and channels implicated in IC/BPS

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Mitochondrial-Nuclear Communication: Under conditions of metabolic stress or exercise, MOTS-c translocates to the nucleus, where it regulates the expression of nuclear genes associated with stress adaptation and homeostasis

Consequently, the results of this more conservative analysis were compared with our main results as a sensitivity analysis